A review of injectable and implantable biomaterials for treatment and repair of soft tissues in wound healing

Shih Feng Chou, Simi Gunaseelan, Mhd Hussam Hijazi Kiellani, Venkata Vamsi Krishna Thottempudi, Pierre Neuenschwander, Huarong Nie

Research output: Research - peer-reviewReview article

Abstract

The two major topics concerning the development of nanomedicine are drug delivery and tissue engineering.With the advance in nanotechnology, scientists and engineers now have the ability to fabricate functional drug carriers and/or biomaterials that deliver and release drugs locally as well as promote tissue regeneration. In this short review, we address the use of nanotechnology in the fabrication of biomaterials (i.e., nanoparticles and nanofibers) and their therapeutic function in wound healing as dressing materials. Furthermore, we discuss the use of surface nanofeatures to regulate cell adhesion, migration, proliferation, and differentiation, which is a crucial step in wound healing associated with tissue regeneration. Given that nanotechnology-based biomaterials exhibit superior pharmaceutical performance as compared to the traditional medicine, this short review provides current status and future directions of how nanotechnology is and will be used in biomedical field, especially in wound healing.

LanguageEnglish (US)
Article number6341710
JournalJournal of Nanotechnology
Volume2017
DOIs
StatePublished - 2017

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Biocompatible Materials
Nanotechnology
Repair
Tissue
Biomaterials
Tissue regeneration
Pharmaceutical Preparations
Medical nanotechnology
Drug Carriers
Cell adhesion
Nanofibers
Drug delivery
Tissue engineering
Medicine
Nanoparticles
Engineers
Fabrication
Direction compound
Drug products

ASJC Scopus subject areas

  • Materials Science(all)

Cite this

Chou, S. F., Gunaseelan, S., Kiellani, M. H. H., Thottempudi, V. V. K., Neuenschwander, P., & Nie, H. (2017). A review of injectable and implantable biomaterials for treatment and repair of soft tissues in wound healing. Journal of Nanotechnology, 2017, [6341710]. DOI: 10.1155/2017/6341710

A review of injectable and implantable biomaterials for treatment and repair of soft tissues in wound healing. / Chou, Shih Feng; Gunaseelan, Simi; Kiellani, Mhd Hussam Hijazi; Thottempudi, Venkata Vamsi Krishna; Neuenschwander, Pierre; Nie, Huarong.

In: Journal of Nanotechnology, Vol. 2017, 6341710, 2017.

Research output: Research - peer-reviewReview article

Chou, Shih Feng ; Gunaseelan, Simi ; Kiellani, Mhd Hussam Hijazi ; Thottempudi, Venkata Vamsi Krishna ; Neuenschwander, Pierre ; Nie, Huarong. / A review of injectable and implantable biomaterials for treatment and repair of soft tissues in wound healing. In: Journal of Nanotechnology. 2017 ; Vol. 2017.
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